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Human Liver fibrosis-derived ECM

Human Liver fibrosis-derived ECM

Our Liver Fibrosis-Derived Extracellular Matrix (ECM) is a specialized scaffold engineered to replicate the fibrotic liver microenvironment, providing researchers with a realistic and consistent platform to study liver fibrosis and related pathologies. Derived from fibrotic human liver tissue, this ECM retains the key structural and biochemical characteristics of a fibrotic liver, including an increased collagen matrix density and altered growth factor profile, making it ideal for in vitro studies on fibrosis mechanisms, disease progression, and therapeutic intervention.
This ECM is crafted in batch production to ensure high consistency and quality across experiments, supporting large-scale research and reproducibility. Its fibrotic structure allows for the exploration of cell-ECM interactions that drive fibrosis, enabling researchers to investigate the effects of treatments aimed at slowing, stopping, or reversing fibrosis in a disease-relevant environment. With its physiologically relevant properties, our Liver Fibrosis-Derived ECM is an essential tool for advancing the understanding of fibrotic diseases, enhancing the development of targeted therapies, and providing a valuable model for preclinical drug screening.

12-15 mg/mL protein

1 mL/5 mL

Critical gelation concentration (no cross-linking) - 5 mg/mL

Characterised for Collagen I, II, III, IV, fibronectin, elastin, laminin, and other essential proteins

Minimal lipid/DNA content

Sterile, HIV/HBC/HCV-free

ECM-LIV-F

Characteristics
Applications

ECM remodelling

In vitro disease modelling

Tissue Engineering

CoA sample

Handbook

Supply options

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