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Human Liver S9 fraction (pool-100)
Our 100-donor pooled human liver S9 fractions deliver an enriched and highly representative model for evaluating drug metabolism, covering both Phase I and Phase II metabolic pathways. With S9 fractions pooled from 100 individual donors, this product captures an extensive diversity of enzymatic profiles, providing a comprehensive system for drug discovery and preclinical assessments.
Specifications
Suited for
Metabolic stability (Phase I/II)
10 mg of protein/vial, 1 mL
Batch size >1000 vials
Total CYP > 90 ng/mg of protein
Phase II enzymes characterised
Measured CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2E1, CYP3A4/5 within population average levels
Filtration-sterilized
Metabolite Identification
Ames assays
Price (1-100) vials
$95
Price (>100) vials
$71
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