Pooled Human Hepatocytes (10-donor pool)
Pooled human hepatocytes are essential for assessing the metabolic stability of various compounds and play a crucial role in drug discovery. Our hepatocytes, sourced from 10 donors and produced in big batches (up to 2,000 vials), offer exceptional quality with over 85% viability and stability in culture for 6-12 hours. Pooled Suspension Human Hepatocytes serve as the major toolbox for short-term metabolic stability analysis, incorporating both Phase I (oxidative metabolism) and Phase II (conjugation) enzymes. Since individual donors may exhibit diverse CYP and Phase II levels, pooling is essential for assay reproducibility. Additionally, we provide comprehensive CYP characterization to ensure precise and reliable results.
HEP-S-10
Specifications
- >85% viability upon thawing
- >5 mln cells/vial
- Qualified for the population-average CYP activity
(CYP1A2; CYP2A6; CYP2B6; CYP2C8; CYP2C9; CYP2E1; CYP3A4/5; CYP3A4/5)
- Stable for at least 6 hours in suspension culture
- Sterile; HBV/HCV/HIV-free
Price/vial:
$500