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Human Liver S9 fraction (pool-50)
Our 50-donor pooled human liver S9 fractions provide a balanced and reliable system for evaluating both Phase I and Phase II drug metabolism, offering a versatile tool for early drug discovery and preclinical studies. By pooling S9 fractions from 50 individual donors, this product delivers a representative enzymatic profile, reflecting a diverse range of metabolic activities seen in the human population.
Specifications
Suited for
Metabolic stability (Phase I/II)
10 mg of protein/vial, 1 mL
Batch size >1000 vials
Total CYP > 90 ng/mg of protein
Phase II enzymes characterised
Measured CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2E1, CYP3A4/5 within population average levels
Filtration-sterilized
Metabolite Identification
Ames assays
Price (1-100) vials
$90
Price (>100) vials
$68
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