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Human Liver S9 fraction (pool-50)

Our 50-donor pooled human liver S9 fractions provide a balanced and reliable system for evaluating both Phase I and Phase II drug metabolism, offering a versatile tool for early drug discovery and preclinical studies. By pooling S9 fractions from 50 individual donors, this product delivers a representative enzymatic profile, reflecting a diverse range of metabolic activities seen in the human population.

Specifications
Suited for

Metabolic stability (Phase I/II)

10 mg of protein/vial, 1 mL
Batch size >1000 vials
Total CYP > 90 ng/mg of protein

Phase II enzymes characterised

Measured CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2E1, CYP3A4/5 within population average levels

Filtration-sterilized

Metabolite Identification

Ames assays

Price (1-100) vials 

$90

Price (>100) vials 

$68

User's Manual
Reagents kit
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