Our human brain mitochondria are isolated from ethically sourced, non-diseased human brain tissue and enriched to preserve mitochondrial structure and function. This high-quality preparation provides a specialized in vitro system for investigating energy metabolism, oxidative stress, and mitochondrial dysfunction in the central nervous system (CNS).
Critically, these mitochondria retain enzymatic activity relevant to monoamine metabolism, including the function of monoamine oxidases (MAO-A and MAO-B)—key enzymes involved in the breakdown of neurotransmitters such as dopamine, serotonin, and norepinephrine. This makes the preparation especially valuable for studying neurodegenerative diseases, psychiatric disorders, and CNS-targeted drug mechanisms.
Human brain mitochondria are ideal for use in neuropharmacology, toxicology, and drug screening, particularly for evaluating mitochondrial safety, bioenergetics, and CNS-specific drug interactions.