Our human kidney S9 fraction provides a versatile in vitro system for evaluating both Phase I and Phase II metabolism in renal tissue. Isolated from human kidney homogenate, this fraction contains both cytosolic and microsomal enzymes, making it ideal for studying a broad range of metabolic reactions, including oxidation, reduction, hydrolysis, glucuronidation, and sulfation.
Designed for use in drug metabolism, clearance prediction, and nephrotoxicity assessment, the human kidney S9 fraction offers a reliable and physiologically relevant model for investigating extrahepatic biotransformation in drug discovery and development