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Human Liver Microsomes (Pool-100)
Our 100-donor pooled human liver microsomes offer an advanced and highly representative metabolic model for comprehensive drug metabolism studies. With microsomes pooled from 100 individual donors, this product provides an extensive metabolic profile that reflects a broader genetic and phenotypic diversity, increasing the relevance and predictability of in vitro findings to real-world populations.

Human Liver Microsomes (Pool-100)

SKU: MIC-H100
$105.00Price

  • 10 mg of protein/vial, 0,5 mL
    Batch size >1000 vials
    Total CYP > 200 ng/mg of protein
     

    Verapamil, Clint (uL/min/mg), 3A4 250 350
    Testosterone, Clint (uL/min/mg), 3A4 60 120
    Diclofenac, Clint (uL/min/mg), 2C9 180 360
    Phenacetin, Clint (uL/min/mg), 1A2 20 40
    Imipramine, Clint (uL/min/mg), 2C19 15 35
    Benzydimine, Clint (uL/min/mg), FMO 10  
    Metoprolol,  Clint (uL/min/mg), 2D6 5 15

     

  • Metabolic stability (Phase I)

    Metabolite Identification

    CYP Inhibition

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