Our human lung microsomes are specifically prepared for in vitro studies requiring accurate assessment of pulmonary drug metabolism. Isolated from human lung tissue, these microsomes are enriched in membrane-bound metabolic enzymes, including cytochrome P450 isoforms relevant to lung-specific biotransformation, such as CYP1A. They are essential for evaluating inhaled drug metabolism, extrahepatic clearance, and respiratory toxicity.
Designed to meet the needs of pulmonary drug development and respiratory toxicology studies, our lung microsomes offer high enzymatic activity and consistent lot-to-lot performance, ensuring reproducibility in metabolic assays. Each batch is rigorously tested for protein content and CYP activity, providing a reliable in vitro model for compound screening, mechanistic studies, and regulatory support.