Our human intestinal ECM (hECM) hydrogel, derived from both healthy intestine donors and donors with chronical diseases such Crohn's Disease and Ulcerative Colitis, provides a physiologically relevant extracellular environment for in vitro modeling of liver physiology and pathology. This hydrogel preserves the native biochemical composition, including essential structural proteins, glycosaminoglycans, and signaling molecules, creating a highly representative microenvironment for studying hepatic cell behavior under normal and diseased conditions.
 
Whether you aim to model healthy liver function or investigate disease progression mechanisms like fibrosis, steatosis, chronic inflammation, and metabolic dysregulation, our hECM hydrogel supports a wide range of applications. It is fully compatible with primary human crude intestinal cells, human intestinal enterocytes, and immune cell co-cultures, making it an ideal platform for drug screening, toxicity testing, biomarker discovery, and fibrosis reversal research.
 
Custom formulations are available to tailor ECM composition, stiffness, and disease relevance to meet your specific experimental needs.