Primary human hepatic stellate cells (HSC) are isolated from healthy or diseased human liver tissue and provided in a cryopreserved format to ensure maximum viability and functionality after thawing. These cells play a crucial role in liver physiology and pathology, particularly in processes related to fibrosis, extracellular matrix remodeling, and hepatic inflammation.
 
Our stellate cells retain key phenotypic markers and can be provided in either quiescent or activated states, depending on experimental requirements. They are ideal for use in fibrosis modeling, drug screening for anti-fibrotic therapies, liver disease research, and studying the mechanisms of hepatic stellate cell activation and signaling pathways.
 
To support advanced co-culture systems and complex liver models, isogenic primary human hepatocytes and other non-parenchymal cell types—including Kupffer cells and liver sinusoidal endothelial cells—are also available upon request. This enables the development of physiologically relevant models for translational research and pharmaceutical testing.