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Get into the tumor microenvironment with
ExVivoGel
Human Cells do not live in plastic naturally. Evolution of Cell Biology lead to the development of many tools to study human tissue behaviour. Most of those, however, include unnatural environments, e.g. tissue culture plastic, its surface modification with various proteins or Matrigel.
There is no human-based Extracellular Matrix Product on Market.
Preci presents the line of ExVivoGel products, developed on the basis of human Extracellular Matrix.
Extracellular Matrix
Collagens (I-IV)
Laminin
Fibronectin
Elastin
Various Proteoglycans Hyaluronic acid
ECM incorporates various hormons, which
promote cell growth, tissue regeneration and differentiation.
Complex tumor models, containing heterogeneous
cells can be generated only using external matrix support.
Correct cell-matrix interection promotes right cell
behaviour in vitro.
Discover real tumor microenvironent with ExVivoGel
Human colorectal cancer metastasis
NASH
Sarcoma
Niche Patient-Derived
Products:
Tumor-derived
NASH-derived
Batch Products:
Pooled tumor
samples
Using our internally developed procedure for ECM components isolation we attempt to capture most of the ECM proteins, including collagens, fibronectin, laminin etc. The mixture is available as sol-gel for your cancer studies.
large fibrotic tissue
specimen
lyophilization
washing
mincing
nanofiltration and concentration
gentle collagen depolymerization
Process outcomes highly homogeneous cell-free mixture of polymerizing ECM proteins
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