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ICH M12 Step 4: what's new in DDI studies regulation? The use of Human Hepatocytes
ICH published the final version of the M12 guideline, marking a pivotal step towards standardizing drug-drug interaction (DDI) studies.
Preci LLC
Jul 1, 2024


Solving microsome pooling challenges for Better Reproducibility
Microsome technology significantly enhances our understanding of drug metabolism, playing a crucial role in the development of...
Preci LLC
May 10, 2024


What are the different types of human hepatocytes assays and how are they used?
The safety of newly developed lead compounds is often prioritized over efficacy. Additionally, the efficacy of a drug in a living...
Preci LLC
Jan 19, 2024


Extracellular Matrix - from EHS mouse to human tissue
For three decades already researchers globally use Matrigel and similar products as a solid support for tissues in for in vitro modeling...
Preci LLC
Jul 28, 2023


Human-derived cell models - road to predictive drug activity assays
Simple reliable assays render drug that are clinically useful. We all recall the succesful attempt of James Cook to discover the drug...
Preci LLC
Jul 28, 2023
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