AML-derived cultured cells are malignant hematopoietic cells isolated from patients diagnosed with Acute Myeloid Leukemia (AML). These cells originate from peripheral blood or bone marrow and are either freshly cultured or cryopreserved following short-term or extended in vitro expansion. They retain the key genetic, phenotypic, and functional characteristics of primary leukemic blasts, making them a valuable model for translational research, drug development, and personalized medicine.