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Human Peripheral Blood Macrophages
Human peripheral blood macrophages are differentiated in vitro from CD14⁺ monocytes isolated from peripheral blood mononuclear cells (PBMCs). Cultured with M-CSF or GM-CSF, these cells develop into functional macrophages that model M0 (naive), M1 (pro-inflammatory), or M2 (anti-inflammatory) phenotypes depending on polarization stimuli. 
They exhibit strong adherence, phagocytic capacity, and cytokine secretion, making them highly relevant for research in immune regulation, pathogen interaction, tissue repair, and drug screening.

Human Peripheral Blood Macrophages

$550.00Price
    • 1 mln cells/vial
    • Post-thaw viability - ≥ 80%
    • Morphology - large, flat, spreading cells
    • Source - CD14⁺ monocytes from human PBMCs
    • Culture Type - adherent monolayer

    • Macrophage polarization (M1/M2)

    • Phagocytosis and pathogen interaction assays

    • Cytokine profiling (e.g., IL-6, TNF-α, IL-10)

    • Co-culture with tumor, stromal, or T cells

    • Immunotoxicity and drug screening

    • Tissue repair and regenerative medicine studies

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