Sarcoma-derived cultured cells are primary tumor cells isolated from patient sarcoma biopsies, including both soft tissue sarcomas (STS) and bone sarcomas. These low-passage cultures retain key features of the parental tumors, including their genetic mutations, heterogeneous morphology, and proliferative behavior.
Compared to established cell lines, patient-derived sarcoma cells more accurately reflect the complexity, drug resistance, and clinical aggressiveness of these rare malignancies.
Sarcoma-Derived Cultured Cells
- 1 mln cells/vial
- Post-thaw viability - ≥ 80%
- Morphology - spindle-shaped, polygonal, pleomorphic
- Culture Type - monolayer (adherent) or spheroid (3D)
- Passage Number - early passage (P2–P5)
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Anti-sarcoma drug screening and personalized therapy testing
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Molecular profiling (e.g., RNA-seq, WGS, cytogenetics)
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Functional assays (migration, invasion, clonogenicity)
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Sarcoma subtype-specific biomarker discovery
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Immunotherapy and resistance modeling
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Co-culture with stromal or immune cells
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3D spheroid and PDX model generation
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